Friday October 11, 2024
Arrival and Check-in at Swope
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5:00-10:00
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BBQ Dinner ( club)
Sponsors
Iwaki, Aquaneering, Tecniplast, and Xenopus Express
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Saturday October 12, 2024
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7:00-8:55
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BREAKFAST
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8:40-8:45
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Introduction and Welcoming Remarks (Speck Auditorium)
Jennifer Landino, Coral Zhou, Helen Willsey
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Session 1. Resources
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8:45- 9:00
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Nikko-Ideen Shaidani (Marine Biological Laboratory) Xenopus Mutant Resource
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9:00-9:15
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Dominique Alfandari (University of Massachusetts, Amherst) Producing novel monoclonal antibody to Xenopus, Axolotl and Mouse to improve rigor and reproducibility
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9:15-9:30
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Gary Gorbsky (Oklahoma Medical Research Foundation) Expanding the Toolset: Creation of Novel Xenopus laevis and Xenopus tropicalis Cell Lines and Their Applications in Gene Editing
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9:30-9:45
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Matt Guille (University of Portsmouth) Title TBD
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9:45-10:00
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Aaron Zorn (University of Cincinnati) Title TBD
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10:00-10:15
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Doug Houston (University of Iowa) DSHB: Sharing monoclonal antibodies through open science
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10:15-10:30
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COFFEE BREAK
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Session 2. Development I
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10:30-10:45
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Jakub (Kuba) Sedzinski (University of Copenhagen) Phenotypic profiling of developing mucociliary epithelium
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10:45-11:00
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Rachel Miller (University of Texas Health, McGovern Medical School) Advancing our understanding of kidney development and birth defects using innovative technologies
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11:00-11:15
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Casey Griffin (New York University) Deciphering the mechanisms of Nager syndrome using Xenopus tropicalis
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11:15-11:30
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Pat Kearns (University of Massachusetts, Boston) Title TBD
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11:30-11:45
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Meghan Bullard (He lab, Georgetown University) Title TBD
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11:45-12:00
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Andrea Wills (University of Washington) Deciphering the contributions of carbohydrate and nucleotide metabolism to Xenopus regeneration
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12:00-1:45
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LUNCH
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Session 3. Reconstitution using extracts
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1:45-2:00
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Yasuhiro Arimura (Fred Hutch Cancer Center) Applying cryo-EM to Xenopus egg extract system to elucidate the structural basis of biological events on chromosomes
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2:00-2:15
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Susannah Rankin (Oklahoma Medical Research Foundation) Protein tricks in extracts and embryos
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2:15-2:30
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Jesse Gatlin (University of Wyoming) Title TBD
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2:30-2:45
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Gembu Maryu (Yang Lab, University of Michigan) Visualization and manipulation of Cdk1 oscillations in water-in-oil droplets
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2:45-3:00
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Martin Wühr (Princeton University) Protein turnover measurements in embryogenesis
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3:00-3:30
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COFFEE BREAK
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Session 4. Biophysical and Mathematical Modeling
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3:30-3:45
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Sarah Woolner (University of Manchester) Measuring and applying tension in Xenopus: adventures with Flipper-TR and Lego
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3:45-4:00
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Lance Davidson (University of Pittsburgh) New and improved! Tools to explore extreme mechanics of morphogenesis
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4:00-4:15
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Kristian Franze (University of Cambridge) Measuring and manipulating tissue mechanics to understand brain development in Xenopus laevis
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4:15-4:30
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Shinuo Weng (Johns Hopkins University) TFlux and Flex: Building Insights into Cell and Tissue Mechanics with Useful Fluctuation
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Session 5. Development II
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4:30-4:45
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Adrian Thompson (Brown University) Novel approaches for modeling neurodevelopmental effects of sodium channel dysregulation in the developing brain of Xenopus laevis tadpoles
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4:45-5:00
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Richard Behringer (University of Texas, MD Anderson Cancer Center) Role of anti-Müllerian hormone in Xenopus tropicalis
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5:00-5:15
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David Vijatovic (Sweeney lab, Institute of Science and Technology Austria) Adeno-Associated Viral Tools to Trace Neural Development and Connectivity in Xenopus Frogs
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5:15-5:30
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Vanja Stankic (Chen Lab, University of Texas, MD Anderson Cancer Center) Cell at a Time: Unveiling the Cellular Landscape of Xenopus Lungs During Metamorphosis
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5:30-5:45
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Kris Vlemnickx (University of Ghent)| Modeling human cancer and inherited disease, expanding the experimental landscape to oncogenes and the non-coding genome
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5:45- 6:00
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Can Aztekin (Swiss Federal Institute of Technology Lausanne) Xenopus regeneration and new sequencing approaches
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6:00-8:00
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DINNER
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KEYNOTE
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8:00-9:00
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Thomas Naert (University of Ghent) Non-random DNA repair allows predictable genome engineering
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9:00-11:00
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MIXER @ Captain Kidd
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Sunday October 13, 2024
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7:00-8:45
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BREAKFAST
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Session 6. Omics
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8:45-9:00
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Leonid Peshkin (Harvard University) XePA: Xenopus Protein Atlas
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9:00-9:15
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Hui Chen (University of South Carolina) Quantifying Nascent Transcription in Early Embryogenesis
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9:15-9:30
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Jose Abreu (Harvard University) Xenopus Embryo Atlas: every single cell?
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9:30-9:45
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Taejoon Kwon Lab Student TBD (UNIST) Title TBD
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9:45-10:00
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Nayeli Reyes-Nava (Wallingford lab, University of Texas at Austin) Proteomics, AlphaFold, and disease modeling in Xenopus
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10:00-10:15
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Karel Dorey (University of Manchester) Uncovering the mechanisms underpinning regenerative neurogenesis using single-cell transcriptomics
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10:15-11:00
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COFFEE BREAK
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11:00-12:00
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Junior Strategic Planning
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12:00-1:30
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LUNCH
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1:30-2:30
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Strategic planning (including relay of junior requests)
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Session 7. Physiology and Disease Modeling
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2:30-2:45
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Shiri Kult Perry (Shubin lab, University of Chicago) The Xenopus respiratory system reveals common tetrapod mechanisms for growth, regeneration, and healing.
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2:45-3:00
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Nicole Edwards (Zorn Lab, Cincinnati Children’s Hospital) Discovering the developmental basis of endosome trafficking disorders and congenital anomalies using Xenopus
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3:00-3:15
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Lydia Youmans (University of Texas, Houston) As the Frog Folds: Exploring Human Genetic Variants of Neural Tube Defects in Xenopus
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3:15-3:30
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Mustafa Khokha (Yale University) Are ion channels morphogens? Surprising results inspired by patient based gene discovery.
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3:30-3:45
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Bruno Reversade (A*STAR) Title TBD
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3:45-4:00
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COFFEE BREAK
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Continuation of Disease Modeling
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4:00-4:15
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Adrian Romero (Miller Lab, UTHealth Houston) Bridging tissues: using new technologies in Xenopus to study bone and kidney development
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4:15-4:30
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Jack Govaerts (Schoborg Lab, University of Wyoming) Building a 3D Developmental Atlas of X. laevis with Micro CT
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4:30-4:45
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Engin Deniz (Yale University) Unveiling the complexities of CSF circulation using Xenopus and OCT imaging
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Session 8. Cell Biology
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4:45-5:00
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Saurabh Kulkarni (University of Virginia) Understanding multiciliogenesis in Xenopus
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5:00-5:15
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Enzo Bresteau (Northwestern University) Apical Size Reduction by Macropinocytosis Alleviates Tissue Crowding
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5:15-5:30
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Jaeho Yoon (National Cancer Institute) Limitations of Existing Proximity Labeling Methods and the Development of a New Approach
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5:30-5:45
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Leslie Sepaniac (Bement Lab, University of Wisconsin) Synthetic constitution of traveling Rho GTPase waves at the cell cortex
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5:45-8:00
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DINNER
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KEYNOTE
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8:00-9:00
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Rebecca Heald (University of California, Berkeley) Using Xenopus to investigate the effects of ploidy on cell and developmental biology
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9:00-11:00
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MIXER @ Captain Kidd
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Monday, October 14, 2024
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7:00-9:00
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Breakfast
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9:00-10:30
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XRET GO Jamboree Workshop
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10:30-12:00
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Cryopreservation Workshop and NXR Tour
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12:00
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LUNCH AND DEPARTURE
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